Overweight and obesity are major public health concerns worldwide, with more overweight or obese adults than underweight adults. In 2016, 39% of men and 40% of women aged 18 and over (accounting for nearly 2 billion adults), were overweight, and 11% of men and 15% of women (more than half a billion) were obese worldwide. Both overweight and obesity have shown a marked increase over the past four decades.
Epidemiologic studies have identified high body-mass index (BMI, the weight in kilograms divided by the square of the height in meters) as a risk factor for an expanding set of chronic diseases, including; cardiovascular disease, diabetes mellitus, chronic kidney disease, many cancers, and an array of musculoskeletal disorders. As the global health community works to develop treatments and prevention policies to address obesity, timely information about levels of high BMI and health effects at the population level is needed.
Currently, the effective treatment of obesity includes a reduced-energy intake, increased physical activity and exercise, behavior modification, pharmacotherapy, and surgery. The maximal success rate of these treatments, however, is only 21%, and the most popular method for weight loss is pharmacotherapy. The herbal preparation – ENRGIA ESBELTA, based on green tea leaf extract (polyphenols, catechins, EGCG) also contains Gimnema dry extract (gynemic acid), Garcinia dry extract (hydroxycitric acid), Polygonum cuspidatum dry extract (resveratrol), Wakame seaweed thallus extract (fucoxasthin), Saffron extract (crocines), chromium picolinate.
Green tea extract: contains 95 % polyphenols, 45 % EGCG and 70 % catehins. Catechins from green tea belong to the flavonoid family, which are powerful antioxidants. Among the catechins, EGCG (epigallocatechin-3-gallate) stands out, of which Esbelta even contains 45%. EGCG achieves its positive effects when normalizing the level of glucose and insulin in the blood and helps in the process of losing weight. Also, EGCG has antioxidant and antiinflammatory effects, improves the function of the cardiovascular system (lowers the level of bad LDL cholesterol, lowers blood pressure).
Gimnema dry extract: Gymnemic acids are thought to be responsible for its antidiabetic activity and it is the major component of an extract shown to stimulate insulin release from the pancreas.
Garcinia dry extract: The main bioactive component of this fruit is hydroxycitric acid (HCA). Some authors have suggested that HCA causes weight loss by competitively inhibiting the enzyme adenosine triphosphatase-citrate-lyase. HCA has also been reported to increase the release or availability of serotonin in the brain, thereby leading to appetite suppression. Other postulated weight loss mechanisms include inhibition of pancreatic alpha amylase and intestinal alpha glucosidase, thereby leading to a reduction in carbohydrate metabolism.
Polygonum cuspidatum dry extract: is the best known source of resveratrol, one of the most powerful known antioxidants, and ESBELTA contains as much as 95% of it. Resveratrol is a polyphenol that has anti- inflammatory, antioxidant and anti-cancer properties. In the long term, it helps prevent the development of chronic diseases such as cardiovascular diseases, type II diabetes and cancer. The current meta-analysis demonstrated that resveratrol intake significantly reduced weight, BMI, WC (waist circumference) and fat mass, and significantly increased lean mass.
Wakame seaweed thallus extract: Nutrigenomic studies reveal that fucoxanthin induces UCP1 (uncoupling protein 1) in abdominal WAT (white adipose tissue) mitochondria, leading to the oxidation of fatty acids and heat production in WAT. Fucoxanthin improves insulin resistance and decreases blood glucose levels through the regulation of cytokine secretions from WAT. The key structure of anti-obesity effect is suggested to be the carotenoid end of the polyene chromophore, which contains an allenic bond and two hydroxyl groups. Fucoxanthin, which can be isolated from edible brown seaweeds, recently displayed its many physiological functions and biological properties.
Saffron extract: Saffron (Crocus sativus L.) is a valuable native plant in Iran, especially in Southern Khorasan Province. It contributes to the reduction of body mass index, waist circumference and fat mass values. One of the main ingredients is crocin, which has a beneficial effect on insulin resistance, hyperinsulinemia, dyslipidemia, and hypertension.
Chromium – contributes to the normal metabolism of macronutrients and the maintenance of normal glucose and insulin levels; it also improves lipid levels and has a positive effect on bone health. With a combination of healthy diet and physical activity, ESBELTA is the perfect dietary supplement that will help you reduce fat absorption, lose body weight, and maintain normal blood glucose levels.
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Esbelta’s thermogenic effect aids in the burning of body fat and the loss of body weight during a diet.
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